الفهرس 
Ehrlich Ascites Carcinoma (EAC)Only 14 pages are availabe for public view
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Abstract
Cancer is the second world wide cause of death, exceeded only by cardiovascular diseases (Halahleh and Gale, 2018). It is characterized by uncontrolled cell proliferation, except for haematological cancers, generates an abnormal cell mass or tumor. Also, this primary tumor grows thanks to new vascularization and, in time, acquires metastatic potential and spreads to other body sites, which causes metastasis and finally death (Sarkar et al., 2013a). Cancer is caused by damage or mutations in the genetic material of the cells due to environmental or inherited factors (Pérez and Fernández, 2015). Cancer cells differ from normal cells in many ways that allow them to grow out of control. One important difference is that cancer cells are less specialized than normal cells. That is, whereas normal cells mature into very distinct cell types with specific functions, cancer cells do not. This is one reason that, unlike normal cells, cancer cells continue to divide without stopping (Kalyanaraman, 2017; Pirsaheb et al., 2019). Experimental tumors have great importance in modeling, and Ehrlich ascites carcinoma (EAC) is one of the commonest tumors that referred to as an undifferentiated carcinoma and is originally hyperdiploid, has high transplantable capability, no-regression, shorter life span, rapid proliferation, 100% malignancy and also does not have tumor-specific transplantation antigen (TSTA) (Ozaslan et al., 2011; Sujana et al., 2012; Islam et al., 2014).