الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Klebsiella pneumonia is a facultative anaerobe bacterium from enterobacteriaceae family, which reasons an immense assortment of ailments, which incorporates urinary lot contaminations, cystitis, pneumonia, careful injuries diseases, irresistible endocarditis, and unpretentious contaminations, especially in patients with HIV disease and immunosuppression .
In most recent couple of years, probably the most issue of issue among medical care frameworks is protection from carbapenems among Klebsiella pneumoniae due to expanding dreariness and mortality among hospitalized victims .
Carbapenems are considered as the end line cure of Klebsiella pneumoniae diseases and protection from them is a sublime endeavor for clinicians .
The gander at transformed into completed inside the term from july 2018 to July 2019, Out of 1350 bacterial confines, there have been 133 segregates of k.Pneumoniae we gathered 81 blood tests ,forty sputum tests got from patients battling from signs and side effects and side effects of abatement respiratory parcel disease (e.G.Cough,dysnea and fever), 12 injury tests got from patients tortured by side effects and indications of wound contamination (e.G. Discharge and fistula) . All understanding had been conceded in ICU branch.
Our review figured out that out of 1350 victims ,133 (nine.Nine%) have been klebsiella pneumoniae and 1217 (90.1%) had been different bacterial increment andwere barred from the notice.
All disconnects of okay.Pneumoniae had been presented to 11 exceptional antimicrobial sellers which are commonly utilized inside the Egyptian market in an anti-infection awareness measure these antimicrobial advertisers had been Amikacin (AK 30)mg , Meropenem (MEM 10mg, Imipenem (IPM10mg , Ciprofloxacin (CIP 10mg), Cefaxime (CTX 30mg, Rifampcin (RD 30mg), Tertracyclin (TE 30), Gentamycin (CN10 mg), Ceftriaxone (CRO 30mg), Ceftazidime (CAZ 30mg), Cefotaxime (CTX 30mg) .
Out of 133 klebsiella pneumoniae victims ,35 (26.1%) were carpapenem safe klebsiella pneumoniae and 98 (73.9 %) had been non carpapenenm safe klebsiella pneumoniae .
Worried to safe quality in carpapenem safe disengages blaVIM2 top notch secludes eight/35 , bla KPC1 7/35 , blaKPC2 9/35, blaOXA 48 nine/35 , blaCMY2 7/35 , bla GES 8/35 , bla NDM1 7/35 , blaVIM1 8/35 , blaIMP1 9/35, bla IMP2 0/35 blaCMY1 7/35 .
Blood and sputum tests showed the most noteworthy percent for VIM2 and KPC 1 favorable secludes . Blood tests affirmed the higest rate for KPC2, OXA48 ,CMY2 ,NDM 1 ,VIM 1 ,IMP 1 and CMY 1 decent isolates.Sputum tests showed the absolute best rate for GES .
Relationship between’s extraordinary quality of Meropenem and Imipenem obstruction Klebsiella Pneumoniae . Sublime Correlation betweenbla VIM2 with bla KPC1 , blaCMY2,poor connection of blaVIM2 with blaKPC2, blaOXA48, blaGES blaNDM1, blaVIM1, blaIMP1 and bla CMY1 with huge P expense of blaVIM2 and blaKPC2 . Awful connection betweenbla VIM2 withbla KPC2, blaOXA48, blaGES, bla NDM1, blaVIM1 and blaIMP1 .Bad relationship’s between blakpc1 with blaKPC2, blaOXA48, blaCMY2, blaGES, blaNDM1, blaVIM1, blaIMP1 and blaCMY1 .High-quality relationship among KPC2 with GES and VIM1.Negative connection among blaKPC2 with OXA48,CMY2,NDM1 and IMP1 with colossal P cost among blaKPC2 and blaOXA48 .Fantastic relationship between’s blaOXA48 with blaCMY2, blaGES and bla NDM1.Ngative relationship betweenbla VIM1, blaIMP1 and blaCMY1with extraordinary P esteem among blaoxa 48 and blaIMP1 and significant P cost among oxa 48 and cmy1.High-quality relationship betweenbla CMY2 with blaNDM1 and blaVIM1.Terrible relationship among blaGES with bla CMY2 , blaIMP1 and blaCMY1.Poor connection among blaGES with blaNDM1, blaVIM1, blaIMP1 and blaCMY1 .Negative connection among blaVIM1 and blaIMP1.Wonderful relationship among bla VIM1 and blaCMY1.Advantageous connection between’s bla IMP1 and blaCMY1.
End
Klebsiella pneumonia is a facultative anaerobe bacterium from enterobacteriaceae own family, which reasons a broad assortment of illnesses, alongside urinary parcel diseases, cystitis, pneumonia, careful injuries contaminations, irresistible endocarditis, and unobtrusive diseases, explicitly in victims with HIV tainting and immunosuppression .
In past couple of years, perhaps the most issue of circumstance among medical care structures is protection from carbapenems among Klebsiella pneumoniae because of expanding grimness and mortality among hospitalized victims .
Carbapenems are considered as the last-line cure of Klebsiella pneumoniae contaminations and protection from them is quite difficult for clinicians .
Constant evaluating for antimicrobial weakness designs must be performed to set up forward-thinking antimicrobial polices for cure MDR Klebsiella pneumoniae diseases.
Suggestion
Relentless evaluating for antimicrobial defenselessness styles must be done to lay out refreshed antimicrobial polices for treatment MDR Klebsiella pneumoniae diseases.
Exact solution for diseases ought to be principally founded on individual gamble thing and neighborhood the study of disease transmission and restricted best for genuine contaminations and halted when the defenselessness data are free.
The improvement of a quick investigate stagger on the most extreme fundamental instruments of Carpapenem obstruction is a significant endeavor and should be suggested in comparatively studies as it’s far basic to further develop the executives through a markdown in treatment put off.