الفهرس 
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Abstract
Summary
Preeclampsia (PE) is a common human pregnancy illness having hypertension and proteinuria, both of which occur in the second trimester of pregnancy in a woman who had previously been normotensive.
Preeclampsia is a multisystem disease that progresses over time characterized by the occurrence of proteinuria and hypertension in late pregnancy/postpartum, or hypertension as well as severe dysfunction of end-organ having proteinuria sometimes. Placental and maternal vascular dysfunction cause the condition, which often goes away after birth.
Preeclampsia increases the risk of cardiovascularity late in the life of women. The placenta acts crucially in PE because the disease only occurs when there is placental tissue present, and its signs disappear after delivery.
Preeclampsia is caused by either placental hypoxia, which causes increased oxidative stress and endothelial dysfunction, as well as irregular trophoplstic invasion of uterine vessels (placental cause) or genetic factors.
Non-coding RNAs having 200 nucleotides or more are renowned as long non-coding RNAs (lncRNAs) (Fang and Fullwood, 2016). LncRNAs have a variety of subcellular localization patterns, varying from bright sub-nuclear foci to approximately exclusively cytoplasmic localization; both compartments contain several lncRNAs.
Longnoncoding RNAs (lncRNAs) are thought to be an RNA polymerase II transcriptional noise product with no biological