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Abstract Our research is based on the coronary images resulting from cardiac catheterization.Cardiac catheterization is an operation performed for diagnosis and treatment of cardiovascular diseases.Dye, is injected into the catheter so that the artery can be seen on X-rays.The dye and X-rays make the surgeon able to have a good vision to diagnose..Our objective is to develop an algorithm to enhance the blood vessels in the angiogram sequences using the least amount of dye and X-ray dosage. We started the algorithm by processing the histogram to enhance the global image.This is followed by a multiscale vessel enhancement. Finally, the labelling process is used to remove the artefacts.The outcome of our research satisfied many cardiologists. Our algorithm is additionally tested on peripheral and cerebral vessels and satisfying results are produced. We compared our work with Frangi, the results are better especially in low X-ray dose images |