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العنوان
Analytical approaches for the determination of some selected binary pharmaceutical formulations /
الناشر
Menna Tullah Sameeh Elsayed Elsherbiny ,
المؤلف
Menna Tullah Sameeh Elsayed Elsherbiny
هيئة الاعداد
باحث / Menna Tullah Sameeh ElSayed Elsherbiny
مشرف / Khadiga Mohamed Kelani
مشرف / Mamdouh Reda Rezk
مشرف / Hany Hunter Monir Bebawi
تاريخ النشر
2021
عدد الصفحات
181 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
19/10/2021
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

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Abstract

This thesis focuses on binary pharmaceutical formulations analysis. Two binary mixture were studied.The first one is hyoscine butylbromide (HYS)/ ketoprofen (KTP), while the second is dextromethorphan HBr (DEX) /benzocaine (BENZ). Different analytical methods (spectroscopic and chromatographic) have been discussed and applied on standard drugs and dosage form. This thesis contains 3 parts: Part one: General introduction and literature review. Part two: Determination of hyoscine butylbromide and ketoprofen in their mixture.Section A: Spectrophotometric and Spectroscopic (Coabsorptive, dual wavelength and IR coupled to chemometric methods) Section B: chromatographic (HPLC & TLC) Part three: Determination of dextromethorphan HBr and benzocaine in their mixture. Section A: Spectrophotometric and Spectroscopic (dual wavelength, ratio difference, second derivative and IR coupled to chemometric methods ) Section B: chromatographic (HPLC)