الفهرس 
Title: The Effect of Tranexamic Acid on Blood Loss in Liposuction; a Randomized Controlled Study
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Abstract
Background: liposuction is one of the most common procedures in the practice of plastic surgery. Since it evolved in the 1980s, continuous modifications have been made to the technique and the equipment involved in the surgery in a trial to make it less injurious to the surrounding tissue, and to decrease blood loss so that patients are hemodynamically stable intra and postoperatively. Tranexamic acid (TXA) has long been used for its antifibrinolytic properties that were beneficial in reducing blood loss, need for blood transfusion and hemoglobin DROP in major trauma and surgeries. Its use in plastic surgery, however, is not well established, apart from maxillofacial procedures. In this study, we aim to illustrate the effect of intravenous (IV) and local infiltration of TXA on blood loss in liposuction surgery. Methods: Between April 2019 and April 2021, 90 patients who requested liposuction for various body parts were divided into 3 groups. Control group, IV TXA and local infiltration of TXA. A sample was taken from infranatant and sent for hematocrit calculation. Volume of blood in lipoaspirate was then calculated. Primary outcome: Effect of IV and localtranexamic acid on volume of blood loss in lipoaspirate Secomdary outcome: Effect of IV and local tranexamic acid on bruising intensity Results: Volume of blood loss in lipoaspirate was considerably lower in the TXA group, with 60% decrease in blood loss in comparison with the control group. TXA has also been shown to markedly decrease bruising tendency in post-operative liposuction patients