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Abstract Aim: The aim of this study was to compare accuracy and clinical outcomes between the computers guided versus conventional model surgery in correction of skeletal anterior open bite. Methodology: This work was conducted between October 2017 & December 2020. A total of 18 patients with skeletal AOB; were divided randomly into two equal groups; computer guided model surgery group (study group) treated using CAD/CAM generated surgical cutting template & located holes guides and conventional model surgery group (control group) using inter-occlusal and final wafers.Each group was passed with 2 methods of assessment; 3D cephalometric analysis and world coordinate system. Results: the operation run uneventfully without any complication, the statistical difference between post-operative and the virtual model regarding skeletal open bite was not significant with the mean difference= 0.1457, the average different in control group was statistically significant =11.3143 Conclusions: the vertality of treatment plane trasfere in Computer guided surgery was proved to be more reliable technique for Skeletal open bite than the conventional model surgery regarding the osteotomy level, symmetric movement and vertical discrepancy |