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Abstract Obesity is a major health burden worldwide, and although it was considered a disease of the western world, it seems to have expanded to the developing world. Severe obesity is one of the major problems in the world and is associated with several comorbidities [e.g. cardiovascular disease, metabolic syndrome, type 2 diabetes mellitus (T2DM), infertility, and increased mortality]. Laparoscopic one-anastomosis gastric bypass (LO-AGB), first reported by Rutledge, was proposed as a simple and effective treatment of morbid obesity. MGBP is a modification of the Mason’s loop gastric bypass, with weight loss results similar to laparoscopic Roux-en-Y gastric bypass (LRYGB), which was the most favored bariatric procedure in America. This procedure has also been called one or single anastomosis gastric bypass. However, controversies about the relative safety of this procedure remain, mainly the incidence of marginal ulcer and reflux esophagitis. The current study aimed to assess the effect of laparoscopic mini-gastric bypass procedure on morbid obesity as regard excess body weight loss and obesity related co-morbidity. |