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العنوان
The value of fructosamine in prediction of angiographic outcomes and MACE in diabetic patients presented with anterior ST segment elevation acute coronary syndrome undergoing their first primary PCI/
الناشر
Ain Shams University.
المؤلف
Abo Elnour,Mohammed Borham Borham .
هيئة الاعداد
باحث / محمد برهام برهام أبو النور
مشرف / محمد إسماعيل أحمد
مشرف / رامي ريمون إلياس
مشرف / أحمد إبراهيم الدسوقي
تاريخ النشر
2022
عدد الصفحات
142.p;
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية الطب - Cardiology
الفهرس
Only 14 pages are availabe for public view

from 142

from 142

Abstract

Background: Cardiovascular diseases are the leading most common cause of death in industrialized countries. The chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of different organs especially heart and blood vessels.
Objective: To study the predictive value of Fructosamine as a marker of short-term glycemic control over 2-3 weeks on the angiographic and clinical outcomes in diabetic patients presented with anterior STEMI in Ain shams university hospital.
Patients and Methods: This is an observational study recruiting 100 patients presented with anterior STEMI who underwent their first primary percutaneous coronary intervention (PPCI) from May 2020 to December 2020.
Results: Angiographic results of patients post PCI were as follows:
Regarding Thrombolysis in myocardial infarction (TIMI Flow), 8 patients had TIMI flow 0, 18 had TIMI I, 27 had TIMI II and 37 had TIMI III flow. Regarding myocardial blush grade (MBG) 12 patients had MBG grade 0, 27 had grade I, 20 had grade II and 4 had grade III.
During follow up for one-month, Major adverse cardiac events (MACE) occurred in 56% of patients. Measured serum Fructosamine levels were ranging between (233 to 557 µmoll/L) the results showed a strong correlation between serum Fructosamine and TIMI flow MBG. Patients with higher Fructosamine level had worsen TIMI flow and MBG and more occurrence of MACE in diabetic patients after PPCI.
Conclusion: High Fructosamine level can be used as a predictor for worse outcomes in diabetic patients presented with Anterior STEMI.