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العنوان
Clinico-pharmacological Evaluation of Phoxim Against Rhipicephalus sanguineus in Dogs /
المؤلف
Abd-Elaziz, Aliaa Ali Ibrahim.
هيئة الاعداد
باحث / علياء علي إبراهيم عبد العزيز
مشرف / عبد الفتا ح محمد عبد الفتا ح
مناقش / هشام يوسف محمد
مناقش / وليد فتحي خليل
الموضوع
pharmacology. Veterinary Medicine.
تاريخ النشر
2022.
عدد الصفحات
95 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الحيوان والطب البيطري
تاريخ الإجازة
1/3/2022
مكان الإجازة
جامعة قناة السويس - كلية الطب البيطري - pharmacology
الفهرس
Only 14 pages are availabe for public view

from 119

from 119

Abstract

The present study was designed to evaluate the acaricide efficacy of phoxim and deltamethrin on Rhipicephalus sanguineus in vitro and to evaluate the efficacy of both agents in vivo. In addition, we aimed to establish the current level of acaricidal resistance for the two products commonly used in tick control in dog through: In vitro studies including immersion tests (adult and nymph), larvae packet test and eggs hatchability test. In vivo studies including evaluation of the efficacy of phoxim and deltamethrin on Rhipicephalus sanguineus as well as its effect on hematological parameters via twenty local dogs, that were divided into four groups of dogs, healthy non- infested, infested non-treated, infested treated with phoxim and infested treated with deltamethrin. The results of the present study indicated that the phoxim exhibited significant elevation in mortality % with decreased in resistance % of Rhipicephalus sanguineus adult compared to deltamethrin in both vitro and vivo studies. On the other hand, deltamethrin exhibited significant elevation in mortality % with decrease in resistance % of Rhipicephalus sanguineus nymph and larvae comparing with phoxim in vitro results. Meanwhile, phoxim and deltamethrin showed significant decrease in hatchability % of Rhipicephalus sanguineus eggs. Regarding to the blood parameters, the infested group exhibited significant decrease and increase respectively, in hemogram parameters and (WBCS count and eosinophiles %) compared to the healthy control group. It could be concluded that the phoxim showed a powerful efficiency against the Rhipicephalus sanguineus adult when compared with deltamethrin which attributed to development resistance of adult stage for the latter in vitro and in vivo. On contrary, deltamethrin showed better efficacy against Rhipicephalus sanguineus nymph and larva compared with that of phoxim.