الفهرس 
Title : Screening for Celiac Disease in Children and Adolescent with Autoimmune Thyroiditis
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Abstract
Background: The global prevalence of autoimmune diseases in pediatric age is about 5%. Among them, the most frequent autoimmunities are represented by autoimmune thyroid diseases (AIT). Autoimmune thyroid disease can be associated with other autoimmunities such as celiac disease (CD), diabetes mellitus type 1 (T1DM). Celiac disease is a multisystem autoimmune disorder, which is induced by dietary gluten exposure.Aim: The aim of this study was to screen for celiac disease in children and adolescents with autoimmune thyroiditis. Material and Methods: This cross sectional study was conducted on a total 55 patients with positive anti-thyroid antibodies aged between 3 and 18 years following in the outpatient clinic of Diabetic Endocrine Metabolic Pediatric Unit (DEMPU), Children{u2019}s Hospital Faculty of Medicine Cairo University in the period from April 2019 to March 2020. Age, gender, complaints at the time of presentation, family history of thyroid disorders, clinical and laboratory findings were recorded. All patients were screened for celiac disease by measuring anti-tissue transglutaminase (anti-tTG) IgA antibodies and total serum IgA then upper GIT endoscopy was done for patients with positive celiac serology result. Results: Fifty five patients including 47 females (85.5%) and 8 males (14.5%) were included in this study. Family history of thyroid disease was presented in 29.1% (n=16) of patients. At time of diagnosis with AIT was observed that, 67.3% of patients (n=37) had hypothyroidism, while 29.1% (n=16) had hyperthyroidism and 3.6% (n=2) had euthyroid disease