الفهرس 
Title : Effect of Acupressure on Pain, Fatigue and Anxiety among Patients with Multiple Sclerosis
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Abstract
Back ground: Pain, fatigue and anxiety are common symptoms that disrupt physical, cognitive, emotional, and social functioning of patients with multiple sclerosis. Aim: The aim of the study was to evaluate the effect of acupressure on pain, fatigue and anxiety among patients with multiple sclerosis. Design: Non-equivalent interrupted quasi-experimental (pre-post) control design was utilized to conduct the current study. Sample: A convenient sample of 60 adult male and female patients were selected and randomly divided equally into study group who received acupressure for three times per week for two weeks and control group who received routine hospital care. Setting: Study was conducted at Multiple Sclerosis Research Unit affiliated with one of the biggest University hospital in Cairo, Egypt. Tools: Four tools were used to collect relevant data namely; 1) Demographic and Medical Data Tool (DMDT), 2) Pain Quality Assessment Scale (PQAS), 3) Fatigue Severity Scale (FSS) and 4) Beck Anxiety Inventory (BAI). Results: There was statistical significant decrease of pain mean scores among the study group who received acupressure when compared to control group who received routine hospital care at 1st week and 2nd weeks (t = 3.268, p-value = 0.002 & t = 4.643, p-value = 0.000) respectively and fatigue mean scores at1st week (t = 5.014, p-value = 0.000), 2nd week (t = 8.598, p-value = 0.000) as well as anxiety mean scores at 1st and 2nd weeks (t = 5.130, p-value = 0.000 & t = 7.401, p-value = 0.000) respectively. Conclusion: Appling acupressure could be effective in reducing severity of pain, fatigue and anxiety among patients with multiple sclerosis. Recommendation: Endorse acupressure as a nursing practice for patients with multiple sclerosis in the early course of the disease