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Abstract Objectives & aim of work: The aim of this study is to assess the diagnostic performance of conventional US, colour Doppler & SWE in differentiation between benign and malignant thyroid nodules in patients referred for ultrasound guided fine-needle aspiration cytology (FNAC) and to correlate imaging patterns & values of these lesions with their pathological nature. Background: Thyroid nodules are found very commonly in thyroid imaging. Although a minority of thyroid nodules is malignant, invasive diagnostic procedures are performed to differentiate between benign and malignant nodules. Ultrasound SWE is a promising non-invasive technique in detection of malignancy in thyroid nodules.Patient & Methods: We studied 99 patients with thyroid nodules consists of 79 females and 20 males, with a mean age of 45.9 ± 7.7 years (30-69 years) underwent conventional ultrasound, colour Doppler,SWE & ultrasound guided FNAC followed by surgery if clinically & cytologically indicated. Results: We found that TI-RADS, colour Doppler SWE elasticity indices (EIs) were significantly higher in malignant nodules than in benign one with p value less than 0.05. Combined parallel methods of TI-RADS & colour Doppler as well as TI-RADS & SWE have better sensitivity in detection of malignancy in thyroid nodule than TIRADS alone. Conclusion: Colour Doppler & SWE parameters added to TIRADS score are having a significant diagnostic value nearly similar to invasive FNAC results in detection of thyroid malignancy. So that they can avoid the unnecessary FNAC of the thyroid nodules to rule out the possibility of malignancy |