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العنوان
Development and validation of spectrophotometric and spectrofluorimetric methods for determination of some selected drugs /
الناشر
Shrouk Essam Ahmed Elgmaal ,
المؤلف
Shrouk Essam Ahmed Elgmaal
هيئة الاعداد
باحث / Shrouk Essam Ahmed Elgmaal
مشرف / Yasser Shaker Elsaharty
مشرف / Nadia Mohamed Mostafa
مشرف / Yasser Shaker Elsaharty
تاريخ النشر
2021
عدد الصفحات
200 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
8/3/2020
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Analytical Chemistry
الفهرس
Only 14 pages are availabe for public view

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from 249

Abstract

This thesis is concerned with the analysis of some pharmaceutical compounds. It comprises three parts, part I is about general introduction of cephalosporin, while part II is about the litrature review of cefdinir and stability indicating methods for determination of cefdinir. Part III is concerned with the simultaneous analysis of a binary mixture of phenobarbital sodium and acefylline piperazine in the presence of dosage form additive (methylparaben). Various analytical techniques were used; spectrofluorimetry, spectrophotometry, chemometry, thin layer chromatography (TLC) and high performance liquid chromatography (HPLC).The proposed methods were simple, accurate, and reproducible, which would be feasible, and sensitive for the determination of the studied drugs. The proposed methods were validated according to ICH-guidelines