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العنوان
Immunohistochemical study of PAX5 expression in lymphoid neoplasms /
الناشر
Wael Abdelfattah Mohamed Ibrahim ,
المؤلف
Wael Abdelfattah Mohamed Ibrahim
هيئة الاعداد
باحث / Wael Abdelfattah Mohamed Ibrahim
مشرف / Ahmed Mohamed Yehia Elhennawy
مشرف / Samia Mohamed Ahmed Gabal
مشرف / Mona Salah Eldin Abdelmagid
تاريخ النشر
2021
عدد الصفحات
212 P . :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علم الأمراض والطب الشرعي
تاريخ الإجازة
5/5/2020
مكان الإجازة
جامعة القاهرة - كلية الطب - Pathology
الفهرس
Only 14 pages are availabe for public view

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Abstract

PAX5 is a monoclonal antibody to a nuclear antigen which is expressed in B lymphocytes, the developing CNS, and adult testis, and can be used on formalin-fixed, paraffin-embedded tissue sections. PAX5 was used in this study to assess the expression of PAX5 gene in 60 cases of lymphoid neoplasms. This study showed that 100% of B cell lymphoma and 90% of classical Hodgkin lymphoma included in this study express PAX5. Thus we concluded that PAX5 can be used as a pan B cell marker and to confirm the B cell origin of most classical Hodgkin lymphoma