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العنوان
Synthesis and Applications of Polymer Hydroxyapatite Nanocomposites /
المؤلف
Abouelgalagel, Ebtisam Mohamed Ibrahim.
هيئة الاعداد
باحث / Ebttiisam Mohamed Ibrahiim Abouellgallagell “
مشرف / Nehal Atef Salahuddin
مشرف / Maged Abd El-Tawab El-kemary
مشرف / لايوجد
الموضوع
chemistry.
تاريخ النشر
2022.
عدد الصفحات
188 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الكيمياء
تاريخ الإجازة
15/6/2022
مكان الإجازة
جامعة طنطا - كلية العلوم * - الكيمياء
الفهرس
Only 14 pages are availabe for public view

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Abstract

Recently, drug targeting has been getting much attention by the researchers for treating cancer. Nanoparticles (NPs) as a key tool in targeted cancer treatment have been widely investigated, and they have shown promising potential. A critical advantage in treating cancer with NPs, as NPs featured a smaller particle size and a high surface area, they could enter the blood circulation via the capillaries and pass through the endothelial cell gap and migrate to the tumor site, thus achieving a drug-targeted distribution and enhancing the bioavailability of the drug. Moreover, NPs could control the
release of the drug through the degradation of biomaterial in a long and smooth pattern, ultimately prolonging the eliminating half-life, improving the effective blood concentration, and reducing the dosing frequency.