الفهرس 
Liver fibrosisOnly 14 pages are availabe for public view
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Abstract
Most patients with NAFLD are commonly asymptomatic and often identified incidentally, and the patients come to the clinician’s attention usually because of elevation of liver enzymes. Moreover, the platelet count itself and platelet-related index, such as AP index, APRI index and FIB4 index have been widely used to evaluate the severity of various liver diseases. have attempted to assess of red cell distribution width-to-platelet ratio as a marker of liver fibrosis. Material and methods This prospective study was carried out on selected group of 50 patients, 25 of them who have non-alcoholic fatty liver with liver fibrosis and 25 patients who have non-alcoholic fatty liver without liver fibrosis which is diagnosed by Pelvi-abdominal U/S and fibroscan. All patients had RDW to platelet ratio (RPR) =RDW×100/ PLT (109/L) and Fib 4 score = (Age × AST) / (Platelet count × (square root of ALT). Results: There was a significant increase in RPR% in NAFLD patients with fibrosis in comparison to NAFLD patients without fibrosis. There was also a positive significant correlation between RPR% and BMI, RDW%, HbA1c, fibrosis and FIB4, while there was a negative significant correlation between RPR and platelets. Conclusion: RPR has a good sensitivity of 88%, so it can be employed as a good non-invasive marker for prediction of fibrosis. KEY WORDS: Non-alcoholic fatty liver, NAFLD, RPR, FIB4, Fibroscan.