الفهرس | Only 14 pages are availabe for public view |
Abstract Our study was conducted to assessment the Fracture risk using trabecular bone score in postmenopausal women with type 2 diabetes having vertebral fractures. This study was carried out on 215 postmenopausal women selected from Mansoura specialized hospital and endocrinology clinics during the period from November 2020 to January 2022. Only 100 patients were fit for our exclusion and inclusion criteria and those patients were sorted into four groups each group was 25 patients, (T2DM with VF, T2DM without VF, non-diabetic with VF, and non-diabetic without VF). Statistical analysis of our results revealed the following findings : In a Comparison of oral antidiabetic drugs used in those with and without VF there was a higher proportion of metformin and vildagliptin use in those with VF and a higher proportion of sulfonylurea use in those without VF. However, these differences were not statistically significantly. In a Comparison of DM duration in those with and without VFs, it shows that DM duration (years) was statistically significantly longer in those with VF vs. those without VF. There was a statistically significantly difference in all 4 parameters : positive FH of DM, history of any fracture, hypertension, and radiographic osteopenia between the four study groups. Age, duration of menopause, HbA1c, FRAX-MOPF (%), and FRAX-HF (%) compared to the two non-DM groups, were statistically substantially greater in the two DM groups. |