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Abstract The varying severity of hepatic reserve function is critically important for etiology and pathogenesis of hepatic encephalopathy. This reserve function is commonly evaluated by Child-Pugh score; however this score is limited by the interrelated variables as albumin and ascites, and at the same time by the subjectively evaluated variable as encephalopathy. Recently, new ALBI score was developed, it was widely validated in many reports, this model depends on albumin and bilirubin and it assesses the degree of underlying hepatic reserve function in cirrhotic patients with HCC and has a high performance in prediction of mortality due to liver failure rather than HCC progression. |