![]() | Only 14 pages are availabe for public view |
Abstract Background: Suicide is a fatal act that represents the person’s wish to die. In psychiatry, suicide is a primary emergency. Suicide rates have continued to rise in recent decades, despite ongoing clinical and research efforts for prevention. In 2012, suicide was the second leading cause of death among 15–29 year-olds. Objective: To develop hypothetical, explanatory, and predictive markers of suicidal behavior that can be subsequently tested in a prospective study. Patients and Methods: The present study involved 150 inpatients and outpatients subjects admitted to El Fayioum General Hospital diagnosed with schizophrenia, bipolar disorder, and major depressive disorder. Our goal was to determine the importance of clinical symptoms of those disorders in correlation to the risk of suicidal behavior and assessment the role of NLR as a recent biomarker that could predict the suicidal risk in patients with major mental illnesses. Results: The majority of the depressive subjects had statistically significant hopelessness and negative self-image. While the bipolar group had a significant statistically with suicidal ideation, negative self-image, and hostility. The schizophrenic group was found significantly correlate with suicidal ideation and hostility. In comparing the NLR in suicidal ideation and attempts, our findings are statistically significant correlation to the schizophrenic group and it confirmed by the logistic regression. Finally, suicide remains a major public health problem, nevertheless preventable, and action for its prevention calls for a coordinated multi-sectoral approach. Conclusion: Suicide is a leading cause of death and disease burden worldwide and more than 90% of subjects who commit suicide have a psychiatric illness. The absolute risk of suicide in different psychiatric disorders varies. So, in the current study, we compared three major mental illnesses “schizophrenia, bipolar, and major depressive disorder”. We study the socio-demographic data and severity of symptoms as a risk factor for suicidal ideation and suicidal attempts. Also, study the NLR as a biomarker indicator of suicidal risk in the major mental illness patients. |