الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
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Abstract
Herbal medicines are assuming a great importance in the primary
healthcare of individuals and society. Regrettably, a huge amount of
information, related to complementary medicine, especially those
regarding its efficacy and safety is garnered exclusively from anecdotal
beliefs. Accordingly, we propose to scientifically justify some of the
folkloric use of two Egyptian medicinal plant extracts, namely olive
leaves and Tamarix aphylla. Initially, we ensured the safety of both
extracts through acute oral administration of graded doses up to 4g\kg
in albino mice and Wistar rats of both sexes. Thus, the extracts were
considered generally safe. we also evaluated the peripheral and central
antinociceptive activity using acetic acid-induced writhing reflex and
tail immersion assay, respectively. Both plant extracts at the doses of
100, 200 and 400 mg produced potent analgesic activity in a dosedependent manner, compared to the standard drugs. Then, we evaluated
the capability of both extracts to reduce pyrexia using brewer’s yeast.
Again, both OL and TA produced potent antipyretic activity
comparable with paracetamol (100 mg). Additionally, the antiinflammatory activity was evaluated either in-vivo using the
carrageenan-induced paw edema model or in-vitro using a heat-induced
hemolysis assay. Both extracts produced a significant antiinflammatory effect. Finally, we performed milk-induced leukocytosis
and eosinophilia to prove the anti-allergic activity, which resulted in a
potent reduction in leukocytosis and eosinophilia induced by milk.