الفهرس 
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Abstract
Hypertensive disorders complicating pregnancy describes four types of hypertensive disease: gestational hypertension which characterized with systolic BP equal or more than 140 or diastolic BP equal or more than 90 mm Hg for first time during pregnancy with no proteinuria.
Preeclampsia at which BP equal or more than 140/90 mm Hg after 20 weeks’ gestation with proteinuria equal or more than 300 mg/24 hours or equal or more than +1 dipstick with or without complications. Eclampsia that has the same clinical criteria as Preeclampsia in addition to seizures that cannot be attributed to other causes in a woman with preeclampsia. Preeclampsia syndrome superimposed on chronic hypertension in which new-onset proteinuria equal or more than 300 mg/24 hours in hypertensive women but no proteinuria before 20 weeks’ gestation or sudden increase in proteinuria or blood pressure or platelet count less than100,000/_L in women with hypertension and proteinuria before 20 weeks’ gestation. chronic hypertension BP equal or more than 140/90 mm Hg before pregnancy or diagnosed before 20 weeks’ gestation not attributable to gestational trophoblastic disease.
Pre-eclampsia is a defective trophoplastic invasion lead to diminished perfusion to the fetus and hypoxic environment eventually lead to release of placental debris that incites a systemic inflammatory response which result in multisystem disorders in mother. So it is a disease that affects both mother and fetus.
A group of maternal complications which may incude Severe pre-eclampsia characterized by systolic blood pressure >160 mm/ Hg or diastolic blood pressure>110 mm/Hg, proteinuria ≥+3, elevated creatinine, marked elevated liver enzymes,obvious fetal growth resriction or pulmonary oedema. Imminent eclampsia is diagnosed by development of headache, epigastric pain or visual disturbance.When tonic-clonic seizures occurring in preeclamptic patient and any causes for convulsion other than eclampsia were excluded its known as eclampsia.
The main aim of this study was to assess correlation between pregnancy hypertensive disorders with Maternity and children morbidity and mortality.
This case-control study was conducted in Obstetrics and Gynecology Department, Minia University, Egypt from January 2021 to December 2021. This study was conducted on 500 gravid women with hypertensive disorders as case group and 500 healthy gravid women as control group.
The main results of the study revealed that:
There is no significant difference between the groups regarding age, BMI, and parity.
SBP and DBP were significant higher in cases compared to controls.
There is a significant difference between the two studied groups regarding PLT, ALT, AST, PT, creatinine, and proteinuria.
There is a significant difference between the groups regarding GA, birth weight and Apgar at 1 min.
There is a significant difference between the groups regarding Placental abruption, antepartum hemorrhage, Postpartum hemorrhage, PROM, HELLP, renal dysfunction, pulmonary edema, thrombocytopenia, Manual removal of placenta, and ICU admission.
There is a significant difference between the groups regarding preterm labor, neonatal death, low birth weight and NICU admission.
There is a significant difference between the three studied groups regarding Placental abruption, antepartum hemorrhage, PROM, Postpartum hemorrhage, induced labor, HELLP, renal dysfunction, pulmonary edema, emergency SC, manual removal of placenta, thrombocytopenia, DIC, ICU admission, and maternal death.
Based on our results we recommend for further studies on larger patients and longer period of follow up to emphasize our conclusion.
Conclusion
Hypertensive disorders in pregnancy (HDP) are one of the leading causes of maternal mortality and stillbirths. HDP includes gestational hypertension, chronic hypertension, preeclampsia, and eclampsia. Hypertension (both chronic and during pregnancy) has been identified as a significant cause of morbidity among Haitian women, yet the etiology behind this association is currently unknown. Preeclampsia is defined as pregnancy-induced hypertension, occurring after 20 weeks of gestation, accompanied by new-onset proteinuria, maternal organ- or uteroplacental dysfunction. Maternal organ dysfunction can manifest in symptoms like epigastric pain, visual disturbance, or severe headache. Uteroplacental dysfunction can lead to fetal growth restriction with low-birth-weight infants. There is a significant burden of perinatal, neonatal and maternal adverse outcome associated with hypertensive disorders in pregnancy in the Minia governorate obstetric population and these adverse outcomes were more prevalent in eclampsia compared to the other hypertensive disorders. Regular goal-oriented clinical audit into perinatal morbidity and mortality associated with hypertensive disorders in pregnancy and an active multidisciplinary approach to the management of these disorders in the hospital might improve the clinical outcomes of women with maternal hypertension.