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العنوان
Comparison between sensitivity and specificity Of sonographic features and fine needle aspiration cytology in the diagnosis of nature of the thyroid nodules /
المؤلف
Ezzat, Eman Magdy Gamal El Din.
هيئة الاعداد
باحث / إيمان مجدى جمال الدين عزت
emanmagdygmal@gmail.com
مشرف / أسامة لمعي نخلة
مشرف / مي حافظ عباس
مشرف / سارة عبد الرحمن محمد
الموضوع
Cytodiagnosis. Thyroid Nodule. Needle biopsy. Biopsy, Needle. Cytodiagnosis Methods.
تاريخ النشر
2022.
عدد الصفحات
112 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
الناشر
تاريخ الإجازة
2/10/2022
مكان الإجازة
جامعة بني سويف - كلية الطب - الاشعه التشخصية
الفهرس
Only 14 pages are availabe for public view

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from 113

Abstract

High resolution ultrasonography (USG) is the first‑line investigation in evaluation of euthyroid nodules. Thyroidimaging reporting and data system (TIRADS) is an USG‑based risk stratification system for classifying thyroid nodules. Subjectswith high‑risk category of TIRADS undergo fine needle aspiration cytology (FNAC) and FNAC findings are reported according toBethesda classification. Bethesda categories are used for determining risk of malignancy.
The aim of this study is to compare the ultra-sonographic characteristics of thyroid nodules with the results of ultrasound-guided fine needle aspiration cytology and correlate the imaging pattern guided by TIRADS classification with their pathological nature and their ability to eliminate unnecessary FNAC thyroid nodule.
Our study included 54 patients of which 4 cases had atypical diagnosis on cytology and were excluded from the results of the study.All subjects underwent USG according to TIRADS andFNAC where applicable. histopathology report was available only for the cases underwent surgical excision about 16 cases.
USG is highly sensitive in diagnosing nature of the thyroid nodule but FNA is more specific. It is a minimally invasive method which can be used to distinguish malignant from benign lesions with a high degree of sensitivity. In patient having high risk feature on USG, they need to undergo FNAC and they should undergo surgical biopsy for confirmation.
FNAC and TIRADS both are highlysensitive but FNA is more specific and accuratetest in identifying thyroid malignancy. Among individualUSG parameters, micro‑calcification was most sensitive with p value was statistically significant,taller than wider and hypoechoic nodules were associated with malignant conditions, while hyperechoic nodules were associated mainly with benign conditions.
We conclude that sonography can be helpful in categorization of a nodule in one of TIRADS categories. With minimal invasive diagnostic methods and high sensitivity of TIRADS classification especially in benign conditionsas in TIRADS 1 & 2, as fine needle aspiration biopsy should be performed on thyroid nodules which is suspicious on TIRADSclassificationas in TIRADS 4&5.
The combination of high-resolution ultrasonography TI-RADS classification and US-FNAC (Bethesda classification)can improve the accuracy of malignant thyroid nodules diagnosis.