الفهرس 
Neonatal jaundiceOnly 14 pages are availabe for public view
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Abstract
Five to ten percent of newborns developed jaundice required the management of hyperbilirubinemia. Phototherapy is currently the most widely used form of therapy. However, reports have shown that oxidant/antioxidant balance is also disturbed during such practice, as some results indicated an increased oxidative stress index after phototherapy
This study was conducted on 40 newborns admitted to the NICU of Benha University Hospitals with jaundice for phototherapy.
The mean gestational age in the studied group was 37 ±2 weeks. The mean neonatal age was 7 ±1 days.
Statistical analysis shows that :
• About two-thirds of the neonates (62.5%) were males.
• The most frequent mode of delivery was cesarean section (67.5%).
• The mean birth weight was 2858 ±173 grams.
• Positive consanguinity was reported in 5%.
• The most frequent maternal risk factors were diabetes mellitus, hypertension, and PROM (15.0% for each), followed by hepatitis and polyhydramnios (10.0% for each).
• Neonatal respiratory distress was reported in only 12.5% of the neonates.
• The most frequent maternal blood group was A+ (25.0%), followed by B+ (20%), while the least frequent was B - (2.5%). A+ was the most frequent neonatal blood group (40.0%), followed by AB (25%), while the least frequent was O + (15.0%).
• The mean urea and creatinine were 38 ±12 mg/dl and 0.86 ±0.24 mg/dl, respectively.
• The mean hemoglobin and hematocrit were 16.1 ±2.2 mg/dl and 43.9 ±6.5%, respectively.
• The mean WBCs and RBCs were 12.2 ±3.3 and 4.5 ±0.8, respectively.
• The mean platelet count was 325,525 ±65,664.
• Total and direct bilirubin significantly declined after phototherapy (8.9±1 and 0.7±0.2, respectively) than before phototherapy (17 ±1.1 and 1.1±0.4, respectively) (P-value <0.001 for each).
• The median pro-oxidant significantly increased after phototherapy (52.5) than before it (31.8) (P-value <0.001). In contrast, Antioxidant significantly declined after phototherapy (1.4) than before it (2.2) (P-value < 0.001).
• The median PAB significantly increased after phototherapy (38.3) than before it (14.3) (P-value <0.001).
• PAB percent increase following phototherapy showed a significant negative correlation with total bilirubin percent decrease following phototherapy (r = -0.421, P-value = 0.008).
• There was no significant correlation between PAB percent increase and (age, birth weight, urea, creatinine, decrease in direct bilirubin, hemoglobin, hematocrit, WBCs, platelet, or RBCs.
• PAB percent increase following phototherapy did not show any significant difference according to neonatal gender (P-value = 0.289), mode of delivery (P-value = 0.916), diabetes mellitus (P-value = 0.198), hypertension (P-value = 0.227), PROM (P-value = 0.955), and neonatal respiratory distress (P-value = 0.554).