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Abstract Background: CABG has been established as the standard treatment of complex CAD. Prognostic models have been adopted in medical guidelines and are now widely used to assess risk and guide therapy. We applied Syntax score (SS) II and Euro score (ES) II to patients undergoing CABG to evaluate their predictive performance of early major Adverse cardiac and cerebrovascular events (MACCE) within 30 days. Methods: In the period between April 2018 and September 2019, 300 patients with left main or/and Multivessel coronary artery disease underwent CABG at the Kasr AL Ainy hospitals. Each of the used scores was subdivided into three subgroups: low, Medium and high 2Risk3. The primary end point was early major Adverse cardiac and cerebrovascular events (MACCE) within 30 days of CABG. Results: The Mean (SS) II was 25.99 with a range from 17 to 35 while the mean (ES) II was 1.33 with a range from 0.5 to 8. There was a statistically significant correlation between (SS) II subgroups with Mortality and Morbidity as well as (ES) II with (ES) II displaying more specifity and accuracy regarding short term Mortality and Morbidity. Conclusion: (SS) II has a better discriminative ability but lesser specifity and accuracy than (ES) II |