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العنوان
Role of serum (1,3)-Ý-D-glucan assay in early diagnosis of invasive f ungal infection in pediatric intensive care unit /
الناشر
Huda Ibrahim Suliman Hegazy ,
المؤلف
Huda Ibrahim Suliman Hegazy
هيئة الاعداد
باحث / Huda Ibrahim Suliman Hegazy
مشرف / Hala Mohammed Fouad
مشرف / Hebat Allah Fadel El Gebaly
مشرف / Doaa Mohammed Ghaith
تاريخ النشر
2020
عدد الصفحات
95 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
9/8/2020
مكان الإجازة
جامعة القاهرة - كلية الطب - Pediatrics
الفهرس
Only 14 pages are availabe for public view

from 124

from 124

Abstract

This study shows that critically ill children are at high risk of developing invasive fungal infection in a pediatric intensive care unit. Delaying the appropriate antifungal treatment of Invasive Candidiasis (IC) while awaiting blood culture results has been associated with increased hospital mortality. The Candida score is a useful tool to differentiate critically ill patients, who would benefit from early antifungal treatment (score >3), from those in whom invasive candidiasis is highly improbable (score {u2264}3). One of the developed biomarkers is (1,3)-Ý-D-Glucan (BG), which is a major cell wall component of almost all fungi except for Zygomycetes and Cryptococcus species. Various studies measured different sensitivity and specificity of (1,3)-Ý-D-Glucan (BG)substance