الفهرس 
Comparative study between sugammadex versus neostigmine in pediatric patients undergoing outpatient surgical procedures
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Abstract
Background: Sugammadex offers a good alternative to the conventional decurarisation process currently performed with cholinesterase inhibitors. Sugammadex, which was developed specifically for the aminosteroid-structured rocuronium and vecuronium neuromuscular blockers, is a modified cyclodextrin made up of 8 glucose monomers arranged in a cylindrical shape.The objective of this study is to compare the efficacy of sugammadex and neostigmine on reversing NMB in pediatric patients undergoing outpatient surgical procedures. We hypothesized that sugammadex might have shorter recovery time than neostigmine.Methods: Eighty pediatric patients aged 2{u2013}18 years scheduled for daycase surgical procedures were randomly assigned into two equal groups to receive 2mg/kg sugammadex (group S) or0.05 mg/kg neostigmine and 0.01 mg/kg atropine (group N) as a reversal agent for rocuronium at the end of surgery. Primary outcome was the recovery time [time from starting of sugammadex or neostigmine till reaching train of four (TOF) ratio> 0.9] whereas secondary outcomes included time from NMB reversal to extubation (extubation time), TOFR at fulfilling clinical criteria of extubation after injection of reversal