الفهرس | Only 14 pages are availabe for public view |
Abstract Background and aim: Urinary proteins may help to understand the physiology and diagnose renal dysfunction in sick infants. The renal function in ill full-term newborns with disorders of early neonatal period by means of detecting specific protein biomarkers in the urine was studied. The aim of this study was to evaluate renal function in full-term newborns with disorders of early neonatal period by detecting specific protein biomarkers in the urine (albumin creatinine ratio and beta-2 micro globulin) and renal angina index. Materials and methods: A cross sectional study on 100 full-term newborns was performed including 40 healthy newborns, 30 newborns with clinical signs of moderate disorders of early neonatal period,19 newborns with severe neonatal disorders without acute kidney injury (AKI), and 11 newborns with both severe neonatal disorders and AKI. Renal angina index was calculated. Albumin-creatinine ratio and the urinary concentrations Ý2-microglobulin (UÝ2-MG) were determined by means of laboratory tests |