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العنوان
Combined effect of tamoxifen and simvastatin on ehrlich tumor bearing animals /
الناشر
Mahitab Gamal Hassan ,
المؤلف
Mahitab Gamal Hassan
هيئة الاعداد
باحث / Mahitab Gamal Hassan
مشرف / Azza M. Agha
مشرف / Samia A. Shouman
مشرف / Marwa M. Safar
تاريخ النشر
2020
عدد الصفحات
119 P . :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العلوم الصيدلية
تاريخ الإجازة
22/9/2020
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmacology and Toxicology
الفهرس
Only 14 pages are availabe for public view

from 133

from 133

Abstract

Cancer is considered a disease of multiple etiologies and it may require different forms of treatment as chemotherapy, radiotherapy, target therapy or even surgery. Cancer treatment is upon combination mostly of more than one drug that can act simultaneously on different targets. Therefore, the development of different multi- targeting anti-cancer therapies is of an importance nowadays in attempt to increase efficiency of chemotherapeutic agents and reduce adverse events. Tamoxifen (TAM) is a selective estrogen receptor modulator, which is mainly used for treatment of hormonal positive breast cancer.Simvastatin, an HMG-COA reductase inhibitor with impressive antitumor effects on several models of animal tumors and cell lines