الفهرس | Only 14 pages are availabe for public view |
Abstract Traumatic brain injury (TBI) is the main cause of death and disability more than any other traumatic insult.The aim of the study is to assess Role of Mgso4 as a neuroprotective in patients with moderate or severe traumatic brain injury and to identify if Mgso4 is able to improve clinical outcome and reduce mortality of these patients or not. The study was a prospective, double-blind, placebo- controlled study with randomization.This study included 60 Patients with post traumatic brain injury either moderate ( GCS = 9-12) or severe (GCS = 3-8), randomly divided into two equal groups (30 patients each) ,group (A) received MgSo4 and group (B) received normal saline as a placebo. Patients were regularly monitored and GCS was recorded at day three of trauma,day seven then GOS was recorded after 2 months of trauma.group A (received Mgso4) was associated with statistically significant correlation between GCS on admission and GOS after 2 months.With administration of Mgso4; the better GCS on admission,the better clinical outcome after 2 months |