Search In this Thesis
   Search In this Thesis  
العنوان
Synthesis of arylthiazole derivatives with expected anti-methicillin resistant staphylococcus aureus activity /
الناشر
Inas Galal Mahmoud Shahin ,
المؤلف
Inas Galal Mahmoud Shahin
هيئة الاعداد
باحث / Inas Galal Mahmoud Shahin
مشرف / Azza Taher Taher Shalaby
مشرف / Khaled Omar Ahmed Mohamed
مشرف / Asmaa Elsayed Abdellatief Kassab
تاريخ النشر
2020
عدد الصفحات
129 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
العلوم الصيدلية
تاريخ الإجازة
9/11/2020
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmaceutical Sciences
الفهرس
Only 14 pages are availabe for public view

from 145

from 145

Abstract

This Thesis includes four chapters. The first chapterincludes an introduction about the synthesis of phenylthiazole derivatives and their anti-Methicillin Resistant Staphylococcus aureus (MRSA) activities.The second onedisplays the research objectives and schemes constructed for the synthesis of the new target compounds.The third one consists of the theoretical discussion of the experimental work and antibacterial activity of the new target compounds. The fourth chapter is concerned with the experimental work of preparing the intermediates and the target compounds in details. Moreover, the physical properties of the synthesized compounds, their element analyses and spectral data are elucidated. Additionally, it contains the antibacterial assays, the physicochemical and pharmacokinetic investigations of the target compounds and their molecular docking study