![]() | Only 14 pages are availabe for public view |
Abstract Background: Salivary gland neoplasms (SGNs) are morphologically diverse neoplasms originating from different glandular cell types. They are heterogeneous in nature with variable histology, clinical behavior, and tumor grade. Moreover, specific gene translocations and fusions are associated with some types of SGNs. Aim: The purpose of this study was to evaluate the prevalence of salivary gland neoplasms diagnosed in Cairo’s educational hospitals and to compare the results with findings in the literature. Materials and Methods: Data of salivary gland neoplasms diagnosed between 2010 and 2019 were collected from the files of the Cairo’s educational hospitals. Results: Salivary gland neoplasms in the present study constituted 2.4% of all the 9609 registered oral and maxillofacial biopsies. A total of 231 cases of SGNs were collected and reviewed. Of these, (61.1%) were benign and (38.9%) were malignant. Minor salivary glands (51.94%) were more involved than major ones (45.02%). Pleomorphic adenoma was the most frequent type of benign SGNs (68.8%) while Mucoepidermoid carcinoma was the most frequent type of malignant SGNs (46.7%). The mean age of SGNs was 41.14 ±15.43 years with a slight male predilection. Conclusion: In this study we observed a marked geographic variation in the relative frequency of various salivary gland neoplasms in Cairo government. |