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العنوان
Comparative study between different breast board angles regarding the dose to the organs at risk and patient compliance /
المؤلف
El-saber, Mohamed El-saber Mohamed Ali.
هيئة الاعداد
باحث / محمد الصابر محمد علي الصابر
مشرف / عنايات ابراهيم فهمي
مشرف / سناء على البنهاوى
مناقش / هبة جابر الشريدى
مناقش / جيهان عبد العاطى خضر
الموضوع
Radiation Science. Radiobiology
تاريخ النشر
2022.
عدد الصفحات
80 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الإشعاع
تاريخ الإجازة
3/9/2022
مكان الإجازة
جامعة الاسكندريه - معهد البحوث الطبية - Radiation Science
الفهرس
Only 14 pages are availabe for public view

from 87

from 87

Abstract

The aim of radiation therapy is to give the patient a therapeutic dose of radiation while limiting the side effects induced by the application of the dose to the tissues and vital organs around it. The continuing search to reach an optimum dose delivery has led the field of radiation therapy to create innovative methods that integrate scientific advancements.
Breast cells that have multiplied improperly and increased in size to create a lump or tumor are the source of breast cancer. The common frequent reason of cancer-related fatalities in females is breast cancer, which most typically affects postmenopausal women over 50. Males can develop breast cancer, but it is extremely uncommon—only around 1% of all breast cancer occurrences are in men.
Ionizing radiation is a class of treatment called radiotherapy that destroys malignant cells by damaging their DNA. In addition to being provided after mastectomy, radiotherapy is typically administered following breast conserving surgery. The patient position in each session must be the same position as CT simulation.
This study included 30 patients with breast cancer. For each patient, three radiotherapy planes were being conducted to each patient to study the dose to the organs at risk in the three-breast board angles used. A questioner was being given to each patient to study the most comfortable position. Setup errors were being detected with portal image.
The 3 Degrees deviation in setup errors (lateral, longitudinal, vertical,) detected by portal image were compared with setup errors as guided radiation therapy.
Our results showed that:
 V20 of the lung dose in all breast cancer patients, in right sided breast cancer and left sided breast cancer showed insignificant differences between 5,7.5 and 10-degree breast board angels.
 Mean heart dose, showed insignificant differences between 5,7.5 and 10-degree board angels in all breast cancer patients, in right sided breast cancer and left sided breast cancer.
 Mean dose to other breast in all breast cancer patients, by increasing breast board angles especially at angles 7.5 and 10-degree is significantly decreased. While in right sided breast cancer and left sided breast cancer showed insignificant differences between 5,7.5 and 10-degree board angels.
 Mean dose to other lung in all breast cancer patients, in right sided breast cancer and left sided breast cancer showed insignificant differences between 5,7.5 and 10-degree board angels.
 Comfortability in all breast cancer patients, in right sided breast cancer and left sided breast cancer showed insignificant differences between 5,7.5 and 10-degree board angels.
 Mean dose to other breast showed insignificant differences between 5,7.5 and 10-degree board angels in patient that had modified radical mastectomy (MRM), and patient that had supraclavicular nodes (SC) in right sided breast cancer and left sided breast cancer.
 Mean dose to other breast showed significant differences between 5,7.5 and 10-degree board angels in patient that had breast conservative surgery (BCS), and patient not had supraclavicular nodes (SC), where increasing board angle especially at angles 7.5 and 10 decreases mean dose to other breast