الفهرس 
Complications of liver cirrhosis
Portopulmonary hypertension:Only 14 pages are availabe for public view
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Abstract
Background: Patients with cirrhosis, especially decompensated cirrhosis, are more prone to develop AKI than those without cirrhosis. The syndrome type of AKI (HRS–AKI), a spectrum of disorders in prerenal chronic liver disease, and acute tubular necrosis (ATN) are the two most common causes of AKI in patients with chronic liver disease and cirrhosis. Differentiating these conditions is essential due to the differences in treatment, Aim and objectives; to evaluate the role of adrenomadullin in early detection and confirming the diagnosis of AKI (PRA, ATN, and HRS) in decompensated liver cirrhosis cases. We aim to find a biomarker that can diagnose HRS at an early stage, to enable treatment as soon as possible, Subjects and methods; This study is prospective cohort study, was conducted on 80 patients with acute decompensated cirrhotic patients with acute kidney injury, Result; There is a significant positive correlation between adrenomedullin and Child–Pugh (class B and C), Blood urea nitrogen and Creatinine and significant negative correlation between adrenomedullin GFR, Conclusion; Cases with higher serum adrenomedullin have higher risk of developing AKI among all acute admitted decompensated cirrhotic patients. Notably, serum adrenomedullin help to provide an accurate diagnosis of cases with HRS. In comparison with other markers and clinical condition, this maker are useful to select cases whose can’t be treated as well as estimate terlipressin plus albumin treatment responsiveness among HRS cases. Keywords; Acute kidney injury; Hepatorenal syndrome; Liver cirrhosis; Treatment; Biomarkers; Prognosis.