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العنوان
Epidemiological study on infection with Hepatitis B and C among blood donors at the national blood transfusion center in Burundi /
المؤلف
Kwizera, René.
هيئة الاعداد
باحث / رونيه كويز
مشرف / هانى إبراهيم قناوى
مشرف / فرحة الشناوى
مشرف / محمد يوسف إبراهيم
مشرف / أمانى موبيني
الموضوع
Pharmacy. Hepatitis B. Hepatitis C Blood transfusion - Burundi.
تاريخ النشر
2022.
عدد الصفحات
online resource (59 pages) :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات (المتنوعة)
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة المنصورة - كلية الصيدلة - المناعة والطب التجددى
الفهرس
Only 14 pages are availabe for public view

from 59

from 59

Abstract

The National Blood Transfusion Center (NBTC) is a public institution. It is located in Bujumbura with the general mission of organizing blood transfusion, to implement quality health insurance; to ensure the quality and safety of blood products and their derivatives. In Burundi, the prevention of transmission of hepatitis B and C during blood transfusions is based on the detection of the B antigen (Hbs Ag ) and the hepatitis C antibody (AcHVC) for hepatitis C. Indeed, all blood bags should be tested for hepatitis B and C. The prevalence of these hepatitis was investigated in blood donors from Bujumbura in order to provide recommendations for improving the quality of blood transfusion. MATERIAL AND METHODS : This study aimed to highlight the prevalence of hepatitis in this institution in Burundi for a period from January 1 to June 30, 2016. All donors were included in this study and no report was excluded. Donated blood has been routinely diagnosed for hepatitis B and C, using the ELISA test. The ELISA technique is an immunoassay, as its main purpose is to demonstrate the presence of disease-specific antibodies or antigens in a blood sample. For the detection of the hepatitis B virus, the direct ELISA technique called ””sandwich”” was used and using the reagent called MONOLISA Ag HBs PLUS. The solid phase consists of 12 strips of 8 wells of polystyrene. For the detection of hepatitis C virus, indirect ELISA was used with MONOLISA called ANTI HCV PLUS. RESULTS : In total, 8,993 was tested. Gender was not specified in the reports. 94 donors were confirmed positive for HBV, the prevalence was 1.04%. 101 donors have been confirmed positive for HCV and the prevalence is 1.12%. It should be noted that in the case of positive, the blood bags are directly destroyed. CONCLUSION : The results of our study demonstrate a low prevalence of HBV and HCV within the NBTC, hence the improvement of preventive measures with regard to the selection of donors and the proper use of the ELISA technique as a precision diagnostic tool. The prevalence of viral markers obtained at the NBTC during my work are lower than those of the general population of Burundi, which reflects the efficiency of the selection of blood donors in the center. To maintain this low rate, the NBTC was recommended to continue to make the diagnosis correctly, but also to monitor its donors.