الفهرس 
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Abstract
This work was conducted to investigate the immunostimulant effects of Panax
ginseng and Aloe vera extracts against Salmonella typhimurium infection in rats. A total
of 72 male albino rats were divided into 6 equal groups. group I served as a control
group. group II: received Panax ginseng orally (250mg/kg) for 4 weeks. group III:
received Aloe vera orally (200mg/kg), for 4 weeks. group IV: was infected with
Salmonella typhimurium orally (1.5 x 109cell/count) at 21 day of the experiment. group
V & VI were given Panax ginseng (250mg/kg) and Aloe vera (200mg/kg) respectively
for the whole experimental period and infected with Salmonella typhimurium on day
21 as group IV.
The results showed that Panax ginseng and Aloe vera extracts caused significant
reduction and elimination of bacterial load in feces of infected treated rats and
enhancement in serum microbial activity.
Significant increase in Hb, RBCs and PCV as well as increased WBCs and
lymphocytes count was recorded. Also, they reversed the levels of hepatic and renal
damage markers, modulate decrease cytokines that deteriorated by Salmonella
typhimurium as (TNF, IL-2) and IgA level , enhancement IL-10 Level, phagocytic
activity and Lysozyme activity but T. Lymphocyte transformation increased only in
Panax ginseng group Histopathological examination of liver and kidney tissues was in
concurrence with the biochemical results.
Our results suggest that Panax ginseng extract and Aloe vera extract have prophylactic
e effect and immunomodulatory potentials in rats infected with Salmonella typhimurium.