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العنوان
Impact of serum IL 10 on Early Prediction of Allograft Rejection in Liver Transplantation/
المؤلف
El Deeb,Mai Ahmed
هيئة الاعداد
باحث / مي أحمد الديب
مشرف / أشرف محمود عقبة
مشرف / محمود المتيني
مشرف / رشا محمد ممدوح عبده صلاح
مشرف / إيمان السيد أحمد
مشرف / مريم ماجد أمين
تاريخ النشر
2022
عدد الصفحات
138.p:
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الطب الباطني
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة عين شمس - كلية الطب - Allergy and Immunology
الفهرس
Only 14 pages are availabe for public view

from 138

from 138

Abstract

ABSTRACT
Background: Tissue transplantation is the preferred treatment for end organ failure such as heart, lung, kidney and liver. Unless the donor and recipient of a transplant are genetically identical, the donated tissue is viewed by the immune system of the recipient as non-self.multiple cytokines are involved in this process, however little is known about their predictive role in rejection. IL10 which exhibit anti-inflammatory activity could be used as early predictor of acute rejection.
Objective: The aim of the current study is to evaluate the possible association between serum IL10 level in liver transplant patients and acute allograft rejection.
Patients and Method: This study was conducted on 45 subjects. Patients will be followed up for 2months and they will be further divided into two groups: Those who developed early acute rejection and those who did not develop rejection (controls)
Result: The study included 38 patients did not develop rejection and 7 patients developed rejection. We found unchanged during rejection of the LT of the levels of IL-10
Conclusion: Several studymust be conducted on cytokines on large sample size to prove early prediction of acute rejection