الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Total knee arthroplasty has become one of the most commonly
performed orthopaedic operations for the treatment of end-stage knee
arthritis. Perioperative blood loss is a significant concern for patients
undergoing TKA, controlling blood loss during and after surgery is
important to improve the patient outcome. Tranexamic acid is one of
the several modalities employed to minimize blood loss in patients
undergoing TKA. Tranexamic acid present in several forms IV, IM
and oral.
The most important finding of the present study was that intraarticular
retrograde injection of TA via the drain at the end of the
operation and then clamping the drain for 1 h effectively reduced
postoperative blood loss and thus the need for blood transfusion after
TKA. This method is simple, easy to perform, suitable for these
patients, and understandable for clinicians.
Regarding the perioperative blood loss management in TKR,
intra-articular tranexamic acid (IA-TXA) application has recently
become a popular method due to its excellent efficacy for reducing
post operative bleeding and transfusion requiremen.
We found also a significant correlation between body mass
index, diabetes mellitus, hypertension and postoperative bleeding.