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العنوان
Molecular Biological studies on curcumin and quercetin nanoparticles on ulcerative colitis in rats /
المؤلف
Ahmed, Marwa Mohamed Lotfy.
هيئة الاعداد
باحث / Marwa Mohamed Lotfy Ahmed
مشرف / Sayedat Saad Abdel-Megeed
مشرف / Safaa Ibrahim Mahmoud Khater
مناقش / Sayedat Saad Abdel-Megeed
الموضوع
Biological. curcumin.
تاريخ النشر
2022.
عدد الصفحات
205 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
تاريخ الإجازة
1/1/2022
مكان الإجازة
جامعة الزقازيق - كلية الطب البيطرى - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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Abstract

In the present study, we have evaluated the possible protective effects of liposomal curcumin and nano quercetin in DSS-induced colitis.
This study divided into two experiment, first experiment used 40 clinically healthy mature adult Sprague-Dawley male albino rats, the animals were divided into (4) groups (n=10). The second experiment used 50 clinically healthy mature adult Sprague-Dawley male albino rats, the animals were divided into (5) groups (n=10).
Experimental design 1
Control group: the animals left without any treatment.
DSS group: the colitis induced by DSS administration (3% w/v) in the drinking water of animals for 7 days.
Lip. Cur. prophylactic group: the animals were received the prophylactic liposomal curcumin (10 mg/kg b.wt) for 2 weeks before and during induction orally by stomach tube, then the colitis induced by DSS (3%) in the drinking water of animals for the last 7 days of liposomal curcumin administration.
Lip. Cur. Treated group: the DSS animals were received the non-prophylactic liposomal curcumin (10 mg/kg b.wt) for 2 weeks after induction orally by stomach tube.