الفهرس 
Role of vitamin D receptor polymorphism in hepatic fibrosis progression in acohort of HCV Egyptian patients
AbstractOnly 14 pages are availabe for public view
 |  | from | 111 |  |  |
| | | from | 111 | | |
Abstract
Background and Aim: Several studies explored the association between vitamin D status and liver fibrosis with contradictory results. We aimed to investigate the potential role of vitamin D receptor (VDR) genetic variants in hepatic fibrosis progression in patients with chronic hepatitis C infection. Patients & Methods: This is a prospective that study included fifty patients with chronic HCV infection fulfilled the inclusion and exclusion criteria and who were divided according to their fibrosis stage measured by transient elastography (fibroscan) into mild-moderate stage of fibrosis (< F2) (25 patients group II) and advanced fibrosis (>F2) (25 patients group III) in addition to fifty normal individuals who served as a control (group I). All participants were subjected to full history and clinical examination, routine laboratory investigations, abdominal ultrasound and liver stiffness assessment by fibroscan. In addition to serum analysis of vitamin D and DNA for VDR polymorphism