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العنوان
The prognostic value of Interim PET in pediatric hodgkin lymphoma, National cancer institute, Egypt 2011-2015 /
الناشر
Sally Mahfouz Abdelnaby ,
المؤلف
Sally Mahfouz Abdelnaby
هيئة الاعداد
باحث / Sally Mahfouz Abdelnaby
مشرف / Lobna Mohammed Shalaby
مشرف / Reham Abdelaziz Khedr
مشرف / Hoda Fathy Elsayed
تاريخ النشر
2018
عدد الصفحات
103 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
علم الأورام
تاريخ الإجازة
5/5/2019
مكان الإجازة
جامعة القاهرة - كلية الطب - Pediatric Oncology
الفهرس
Only 14 pages are availabe for public view

from 125

from 125

Abstract

Background: Hodgkin’s lymphoma (HL) is a highly curable malignant disease. Risk-adapted therapy for children with HL is directed toward high survival, minimal toxicity and optimal quality of life. 18F-FDG PET is a well-established surrogate for tumor chemosensitivity early during therapy. The ongoing PET-adaptive clinical trials are testing the hypothesis that a decision can reliably be made on escalating or deescalating therapy based on interim PET results. Aims: In this study we aimed to identify the prognostic role of interim PET in predicting the prognosis of HL in our center. Methods: This is a retrospective, single center study where a total of 140 patients with newly diagnosed Hodgkin lymphoma were enrolled. Only 83 patients were eligible for analysis of interim PET. PET scan was performed at baseline and after two cycles of chemotherapy. Treatment was not changed according to the results of the interim scan. PET scans reports was used using the Deauville five-point scale, blinded to treatment outcome