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العنوان
Optical coherence tomography biomarkers for visual outcome after intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection for eyes with diabetic macular edema (DME) /
الناشر
Pola Saeed Nasr Soliman ,
المؤلف
Pola Saeed Nasr Soliman
هيئة الاعداد
باحث / Pola Saeed Nasr Soliman
مشرف / Amr Abdellatif Osman
مشرف / Gihan Mohamad Shokier
مشرف / Rana Ahmed Abdelfattah
تاريخ النشر
2018
عدد الصفحات
109 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب العيون
تاريخ الإجازة
6/5/2018
مكان الإجازة
جامعة القاهرة - كلية الطب - ophthalmology
الفهرس
Only 14 pages are availabe for public view

from 114

from 114

Abstract

Purpose: To identify Optical coherence tomography (OCT) biomarkers for visual outcome after injection of intraviteal bevacizumab in the treatment of diabetic macular edema (DME). Materials and Methods: Prospective observational study conducted on eyes with DME with central subfield thickness (CST) more than 250 microns. OCT & best corrected visual acuity (BCVA) were done then eyes received three intravitreal injections of bevacizumab then the BCVA and OCT were repeated after one month of the third injection. Results: We found an improvement both functionally and anatomically. Functionally; the pattern of edema especially combined and subretinal fluid can be used as a biomarker for improvement of vision. Anatomically; subretinal fluid can be used as a biomarker for decrease of CST. Conclusions: The pattern of edema could be used as a reliable biomarker for the visual outcome in eyes with DME and the subretinal fluid is another biomarker that could be used to predict both the functional response as well as anatomical improvement of DME after the bevacizumab therapy