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Abstract The aim of this study is to evaluate the impact of using Anisotropic Analytical Algorithm (AAA) and Acuros XB algorithm (AXB) with its both reporting systems AXB-Dm and AXB-Dw in clinical plans of IMRT and RA techniques for Nasopharyngeal, Prostate and Lung patients. Six plans of different algorithm-technique combinations are performed for each patient in order to evaluate the physical parameters extracted from the Dose Volume Histogram (DVH) for PTVs, Organs at Risk (OARs), monitor units and calculation time. All investigated algorithm-technique combinations give good coverage in all of the studied treatment sites. The main difference can be seen in the number of MUs and calculation time parameters. The use of AXB is thus recommended in calculating RA plans in order to save time at a number of MUs comparable to IMRT, while AAA algorithm is preferable when calculating IMRT plans. For all three treatment sites (H&N, prostate and lung), IMRT plans give significantly (p<0.05) better (lower) D2% than RA plans, no matter what the algorithm is. This can be considered an advantage for using IMRT over RA. TLD measurements on different treatment sites show that, except for bone, there is no obvious difference between algorithms even in air regions.These acceptable differences reflect the convergent behavior of AAA and AXB-Dm or AXB-Dw (although the slight differences in bone region which show that AAA and AXB-Dw overestimate the dose compared to AXB-Dm). |