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العنوان
Phytochemical and biological studies of breynia disticha J. R. forst and G. forst and phyllanthus acidus skeels, Family phyllanthaceae, cultivated in Egypt /
الناشر
Mohamed Magdy Mohamed Hussein Ayoub ,
المؤلف
Mohamed Magdy Mohamed Hussein Ayoub
هيئة الاعداد
باحث / Mohamed Magdy Mohamed Hussein Ayoub
مشرف / Seham Salah Eldin Elhawary
مشرف / Nagwa Mohammed Ammar
مشرف / Rehab Mohamed Seif Eldin Ashour
تاريخ النشر
2018
عدد الصفحات
233 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
العلوم الصيدلية
تاريخ الإجازة
19/5/2019
مكان الإجازة
جامعة القاهرة - كلية الصيدلة - Pharmacognosy
الفهرس
Only 14 pages are availabe for public view

from 287

from 287

Abstract

The acute toxicity of breynia disticha J. R. Forts and G. Forts and phllanthus acidus skeels successive extract showed safety of oral administration to 2g/kg. The successive methanolic and 70% aqueous methanolic extract showed antioxidant activity indicating that the most promising activity was detected in the polar fractions. Upon studying the polar fraction of breynia distichaJ. R. forts and G. forts and phyllanthus acidus skeels showed significant hepatoprotective activity. Pathological results revealed that Breynia distichaJ. R. forts and G. forts and phyllanthus acidus skeels polar fractions are capable of repairing hepatic tissue and reduced toxic effect of CCL4.The results of the anti-inflammatory activity revealed that the dichlromethane extract of both plants showed potent significant anti-inflammatory activity more than indomethacin used. However the results of the analgesic activity of both plants revealed that the dichloromethane fraction of Phyllanthus acidus Skeels decreases the number of writhing more than the other fractions and in case of Breynia disticha J. R. Forts and G. Forts the petroleum ether fraction decreases the number of writhing more than indomethacin used. Investigation of the lipoidal matter of bioactive petroleum ether fraction of aerial parts of Breynia disticha J. R. forst and G. forst and phyllanthus acidus skeels revealed the presence of saponifiable and unsaponifiable matter