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العنوان
Evaluation of a shorter duration prophylactic antibiotic protocol in the treatment of bone and soft tissue tumours /
الناشر
Mohamed Kamal Nazeer Mohamed ,
المؤلف
Mohamed Kamal Nazeer Mohamed
هيئة الاعداد
باحث / Mohamed Kamal Nazeer Mohamed
مشرف / Walid Atef Ebied
مشرف / Wessam Gamal Eldin Abousenna
مشرف / Walid Atef Ebied
تاريخ النشر
2019
عدد الصفحات
121 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة العظام والطب الرياضي
تاريخ الإجازة
10/6/2019
مكان الإجازة
جامعة القاهرة - كلية الطب - Orthopedic Surgery
الفهرس
Only 14 pages are availabe for public view

from 140

from 140

Abstract

Background: Surgical site infection, especially in surgeries for musculoskeletal tumors, poses a considerable challenge for the orthopedic surgeon. The challenge stems from the high incidence of infection complications encountered after the reconstruction methods include allografts, tumor endoprostheses, and allograft-prosthetic composites. Aim: To evaluate the effectiveness and difference of short duration and long duration antibiotic prophylaxis in minimizing infection rate after bone and soft tissue tumor surgery. Materials and methods: A prospective randomized control trial study was conducted involving 76 patients divided into two groups. Each group divided into two subgroups; subgroups of benign tumor group (B group) and subgroups of malignant tumor (M group). The patients received preoperative prophylactic antibiotic dose of cefoperazone-sulbactam and re-dosing in case of blood transfusion or / with operative duration exceeding 3 hours, and then received postoperative doses of cefoperazone-sulbactam according to randomly selected groups and patients clinically followed-up for three months postoperatively