الفهرس 
Title: The additive role of dynamic contrast enhanced MRI and diffusion weighted MRI in the pre-operative staging of breast cancer
AbstractOnly 14 pages are availabe for public view
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Abstract
Purpose: Our aim is to emphasize the additive role of the dynamic contrast enhanced MRI (DCE-MRI) combined with the diffusion weighted MRI (DWI-MRI) over the sonomammography in the preoperative staging of breast cancer for better management decision and hence better outcome. Methods and Materials: Our study included 50 patients with malignant breast lesions. They were divided into 2 groups: patients who underwent upfront surgery and patients who had received neo-adjuvant chemotherapy. They all performed sonomammography, dynamic contrast enhanced MRI (DCE-MRI) combined with diffusion weighted imaging MRI (DWI-MRI). Results: The results have been compared with final postoperative surgical pathology. Of the 50 patients, 37/50 (74%) cases underwent upfront surgery, while 13/50 (26%) cases had received neo-adjuvant chemotherapy before surgery. In the upfront surgery group, regarding the size of the lesions, DCE-MRI was found to have the highest correlation with the postoperative pathology size. Regarding the axillary lymph nodes status, the overall accuracy measures of sonomammography were higher than DCE-MRI and DWI-MRI, while regarding lesions multiplicity, the accuracy measures of DCE-MRI was found to be higher than sonomammography, while DWI-MRI could not assess lesions multiplicity