الفهرس | Only 14 pages are availabe for public view |
Abstract Introduction: Adolescence is a period of major physiological and psychological changes.Teenagers with T1DM have the additional burden of diabetes management. Patients and methods:This Cross sectional study was conducted to assess the effect of puberty on the glycemic control of adolescent type 1 diabetic females who are being managed and followed up at DEMPU at Abul-Reech Children{u2019}s Hospital of Cairo University and assess the effect of menstruation on insulin demand and blood sugar control in menstrual females. It was conducted on thirty adolescent (menstruated) B4 or B5 girls, thirty prepubertal girls and thirty peripubertal boys T2 to T5, the three groups aged (10-15 years) clinically diagnosed with type 1 diabetes mellitus. Results:We found that mean blood glucose and HbA1c were significantly higher in pubertal females compared to prepubertal females and peripubertal males (p<0.05). In addition mean blood glucose and mean insulin dose during the week of menses were significantly higher than week before menses for pubertal females (p<0.05). HbA1C was higher in girls with irregular menses than in those with regular menses but the difference was not significant |