الفهرس 
Effect of various stabilizers on efficacy of live attenuated brucella RB51 vaccine
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Abstract
Brucellaabortusstrain RB51 is a cattle vaccine that is approved for use in the U.S. for prevention of brucellosis. At the present time,Egypt is considering the use of SRB51 vaccine in their brucellosis control programs. In the current study, the effect of five stabilizing media, on the viability of lyophilized SRB51 over a 52 week period and the characteristics of the immune responses triggered by vaccination with locally prepared RB51 vaccine are determined. 5 groups of mice immunized with the prepared RB51 vaccines and subsequently challenged with high virulent B.abortus544 were protected from reinfection. Post vaccination, the early production of gamma interferon seems to have the prominent role in inducing an immunologically based protection