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العنوان
Different FDG PET/CT parameters in assessment of therapy response in pediatric patients with Ewing family of tumors /
الناشر
Gihan Essam Eldin Elhennawy ,
المؤلف
Gihan Essam Eldin Elhennawy
هيئة الاعداد
باحث / Gihan Essam Eldin Elhennawy
مشرف / Hosna Mohamed Moustafa
مشرف / Walid Soliman Omar
مشرف / Naglaa Abdelreheem Elkinaai
تاريخ النشر
2019
عدد الصفحات
144 P. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
26/9/2019
مكان الإجازة
جامعة القاهرة - كلية الطب - Nuclear Medicine
الفهرس
Only 14 pages are availabe for public view

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Abstract

This is a prospective study of 58 patients with pathologically proved Ewing sarcoma . Multiple PET imaging parameters have been used to predict histologic response. Our study showed 90% reduction in TLG is predictor of histological response while other PET parameters do not predict histological response including SUVmax . Also , it showed that 60 ml pre-local control TLG value is an appropriate cut off for prediction of histological response . Results : PET/CT is superior to conventional metastatic work-up in initial staging with higher sensitivity . 90% reduction of TLG at the threshold of hepatic reference SUVmean can predict poor histological response . Cut off SUVmax{u2264}2.5 can predict histological response with wide confidence interval