الفهرس 
Title : Control of Mycobacterium tuberculosis and activity by ELF-EM pulses at Resonance Frequency
AbstractOnly 14 pages are availabe for public view
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Abstract
Tuberculosisas a major worldwide human disease, caused by Mycobacterium tuberculosis (MTB), is the second most fatal infectious disease after AIDS and one of the most prevalent pathogen that is responsible for socioeconomic disaster for millions of people than any other microorganism. For this purpose, MTB strain H37Rv was exposed to different square electric pulses of extremely low frequency (ELF) generated between two parallel plate electrodes, at different frequencies in the range 0.1 to 1Hz for a period of 30 minutes.The field strength between the electrodes was 400V/m. from the growth characteristics of the microbe for control (non-exposed) and exposed samples, it was found that maximum inhibition in the growth characteristic of the microbe occurred for samples exposed to 0.6 Hz for 45 minutes. Transmission electron microscope (TEM) examination of the treated samples as compared with control indicated remarkable morphological changes in the cell walls and inter-constituents of microbe. Antibiotic Sensitivity test indicated significant increase in theinhibitors for protein synthesis susceptibility, cell wall biosynthesis and RNA as the result of exposure. It was concluded that this new non-invasive treatment of MTB is a promising technique to treat and resist this disease